Group Members

Maria Meißler
Graduate chemist

Group of Prof. Börner
Department of Chemistry
Humboldt-Universität zu Berlin
Brook-Taylor-Str. 2, 12489 Berlin

Lab: 3'117
Phone: +49 (0)30 2093-7464
Email:
maria.meissler
    
chemie.hu-berlin.de
Maria Meißler

Curriculum Vitae

07.09.1986 born in Berlin [GER]
10/2006-12/2011 Chemistry studies at Humboldt-Universität zu Berlin [GER]
02/2010-11/2011
 
Undergrade student at Humboldt-Universität zu Berlin in the group of Prof. Dr. Hans G. Börner
02/2011-12/2011


Diploma research thesis at Humboldt-Universität zu Berlin under guidance of Prof. Dr. Hans G. Börner
Topic: Synthetic model system for a semi-biosynthesis approach to peptide-polymer conjugates
since 02/2012


 
Doctoral research at Humboldt-Universität zu Berlin under guidance of Prof. Dr. Hans G. Börner
Research topic: Enzyme-triggered bioconjugate adsorption and antifouling coatings
Collaboration: Henkel AG, department Adhesive Research
   
   

Research Topic

We are focusing on the processing of peptide-polymer conjugates to generate specific surface coatings. Thereby, enzyme-based mechanisms such as proteolytic cleavage of non-adhesive precursors were used to trigger bioconjugate adsorption. The resulting coatings are able to reduce nonreversible proteins interactions significantly and offer potentials for antifouling surfaces that can be useful for biomedical applications.

 
 M. Meißler, A. Taden, H. G. Börner, Enzyme-Triggered Antifouling Coatings: Switching Bioconjugate Adsorption via Proteolytically Cleavable Interfering Domains, ACS Macro Lett. 2016, 5, 583-587.

doi: 10.1021/acsmacrolett.6b00072

 

Publications

1. M. Meißler, S. Wieczorek, N. ten Brummelhuis, H. G. Börner, in Bio-inspired Polymers: Synthetic Aspects of Peptide- and Protein-Polymer Conjugates in the Post-click Era, Eds.: N. Bruns, A. F. M. Kilbinger, The Royal Society of Chemistry, Cambridge [UK], 2017, pp. 1-30.
doi: 10.1039/9781782626664-00001 ISBN 978-1-78-262423-4
2. A. Taden, K. Landfester, R. Breves, H. G. Börner, L. Breucker, C. Kastner, B. Veith, M. Meißler, H. Keller, Aqueous peptide-functionalized polyurethane dispersions.
WIPO Patent Application WO/2016/135162
3. M. Meißler, A. Taden, H. G. Börner, Enzyme-Triggered Antifouling Coatings: Switching Bioconjugate Adsorption via Proteolytically Cleavable Interfering Domains,
ACS Macro Lett. 2016, 5, 583-587.
doi: 10.1021/acsmacrolett.6b00072
4. T. Pauloehrl, G. Delaittre, M. Bruns, M. Meißler, H. G. Börner, M. Bastmeyer, C. Barner-Kowollik, (Bio)molecular surface patterning by photo-triggered oxime ligation,
Angew. Chem. Int. Ed. 2012, 52, 9181-9184.
doi: 10.1002/anie.201202684